Jason Kang, a 27 year old n/a from Thornhill asks on February 23, 2002,If a person was to experience continous pain, of moderate intensity, for a week, is there any evidence of physiological changes in the body solely due to experiencing pain? If so, is it possible to objectively measure this physiological change? In this case, think of the pain as a tooth-ache.
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There ae many physiological changes which occur with pain, from increased heart rate, blood pressure and autonomic responses (sweating, respiration increases, etc) to chemical changes such as releases of endorphins (several types), serotonin, adrenalin (epinephrine) and noradrenalin (norepinephrine). This altered biochemistry can mess up a lot of things, including sleep patterns, autonomic function, activity levels. In turn, this can create other biologic changes. You can see that it would be hard to identify which effects are caused by pain exclusively. But that really doesn't matter, because all of these things happen when you get pain, especially for long periods, so you will never see one problem in isolation.
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