Adolfo J. de Bold Medicine

Biochemist; Discovered that the heart produces a hormone, the Atrial Natriuretic Factor (ANF)

The Story

As an undergraduate de Bold studied at the National University of Cordoba, Argentina. In 1968, he came to Canada where he received his MSc and PhD at Queen’s University in Kingston, Ontario, in Pathology. In 1973, he was appointed Assistant Professor of Pathology there. Although de Bold trained primarily in biochemistry, he also studied experimental pathology. He used his combined skills to look at the cell biology of the mammalian atrial cardiocyte (heart muscle cell) which culminated in 1980 with the discovery of Atrial Natriuretic Factor (ANF)—a polypeptide hormone produced by the cardiac muscle cell of the heart atrium. He thus demonstrated that the heart has an endocrine function and opened a field of research that has led to many new insights in biology. Besides receiveing many awards for his work, de Bold was also nominated for a Nobel Prize.

Source: de Bold, personal communication

Photo: University of Ottawa department of pathology

 

Career Advice

Biochemist; Professor of Pathology and Physiology and Director, Cardiac Cell and Molecular Biology Laboratory, University of Ottawa Heart Institute

The Person

Birthdate
February 14, 1942
Birthplace
Parana, Argentina
Residence
Ottawa, Ontario
Title
Professor and Director of the Cardiovascular Endocrinology
Office
University of Ottawa Heart Institute
Status
Working
Degrees
  • BSc National University of Córdoba, 1968
  • MSc Queens University, Kingston, ON, 1972
  • PhD Queens University, Kingston, ON, 1973
Awards
  • McLaughlin Medal, 1988
  • Gairdner Foundation International Award, 1986
  • The Ernest C. Manning Principal Award
  • CIBA Award in Hypertension Research
Last Updated
October 13, 2011
Popularity
36483
Personal Webpage Profile viewed 36483 times

Other scientists who may be of interest: