Jamie Scott Microbiology and Immunology

microbiology, immunology

The Story

Works on the molecular basis for antigen recognition by antibodies using peptide as probes of these interactions.

Career ideas:

  • Microbiologists and cell and molecular biologists research such areas as bacteria, fungi, viruses, tissues, cells, pharmaceuticals, and plant/animal toxins.
  • People in this group work in:
  • Biotechnology, chemical, pharmaceutical, food, health care, resource, environmental, and consulting companies, Government
  • Educational institutions, universities/research institutes, Forestry/agricultural sectors.
  • Learn more at <a href="http://www.jobfutures.ca/noc/212p1.shtml#section1_3">Job Futures Canada</a>.

The Person

Microbiology Professor
Simon Fraser University
Last Updated
September 26, 2001

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question #8664

<p>During Biology study, an idea clicked in my head about AIDS. We say that HIV virus cannot be destroyed by drugs, and the vaccine has no effect. On Wikipedia I saw diagrams of the internal structure of the HIV virus and its divisions etc. So it tends my mind to say by using restriction endonucleases, scientists can make genetical changes in the virus HIV. The idea in my mind is to use the HIV virus against itself. Why can't HIV virus be our antibody? Again I make one assumption, that if I am human I have genes representing me as human, i.e the gene says: that particular being is human. If same is the case with HIV virus, then can we change that particular gene? Can the gene representing virus as virus be replaced by gene representing human as human? And the factor which differentiates somatic cells from antobodies be introduced in that HIV virus? If such thing is possible then HIV virus is of my body, call it HIV1, and it will fight for me against every foreign body. And if any HIV virus enters my body, HIV1 will fight against foreign HIV virus. The same that happens when a tiger grows up in a dog family fights with forest tigers. I assume that HIV1 attacks HIV virus with equal intensity. Possibly my idea is total rubbish, but the purpose of this question is to understand the genetics and to see if this can work.</p>

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